Hypogonadism refers to a condition in which the body does not produce enough testosterone. This occurs when the testes or ovaries do not function properly due to a problem with the pituitary gland or hypothalamus. Symptoms of hypogonadism differ between males and females: Males - Reduced sex drive and erectile dysfunction - Loss of body and facial hair - Development of breast tissue (gynecomastia) - Hot flashes - Low sperm count and infertility - Loss of muscle mass - Increased body fat - Fatigue - Mood changes like depression Females - Irregular periods or absence of periods (amenorrhea) - Reduced pubic and armpit hair - Hot flashes - Vaginal dryness - Fertility issues - Loss of bone density (osteoporosis risk) Causes differ between the two types: Primary hypogonadism stems from a problem within the testes or ovaries. This could involve conditions present from birth, infections, radiation treatment, chemotherapy drugs, tumors, or other damage to these organs. Secondary hypogonadism originates from a problem with the pituitary gland or hypothalamus in the brain. These glands produce hormones that signal the gonads to produce sex hormones. Issues with them can disrupt signaling. For testing, blood tests check testosterone levels. Additional hormone tests help determine the origin of the issue. Genetic testing can diagnose certain inborn conditions. Treatment aims to replace missing hormones. Options differ based on age, symptoms, and plans to have children.